1. National Health Service. Stress - Every Mind Matters [Internet]. nhs.uk. NHS; 2021. Available from:
https://www.nhs.uk/every-mind-matters/mental-health-issues/stress/2. Jaysing Salve, Pate S, Debnath K, Deepak Langade. Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study. Cureus [Internet]. 2019 Dec 25 [cited 2023 Nov 6]; Available from:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6979308/3. Gopukumar K, Thanawala S, Somepalli V, Rao TSS, Thamatam VB, Chauhan S. Efficacy and Safety of Ashwagandha Root Extract on Cognitive Functions in Healthy, Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study. Hughes C, editor. Evidence-Based Complementary and Alternative Medicine. 2021 Nov 30;2021(1):1–10.
4. Langade D, Choudhary B, Shetty A. Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory endurance in healthy athletic adults. AYU (An International Quarterly Journal of Research in Ayurveda) [Internet]. 2015;36(1):63. Available from:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687242/5. Arumugam V, Vijayakumar V, Balakrishnan A, B Bhandari R, Boopalan D, Ponnurangam R, et al. Effects of Ashwagandha (Withania Somnifera) on stress and anxiety: A systematic review and meta-analysis. EXPLORE. 2024 Nov;20(6):103062.
6. Jackson PA, Forster J, Khan J, Pouchieu C, Dubreuil S, Gaudout D, et al. Effects of Saffron Extract Supplementation on Mood, Well-Being, and Response to a Psychosocial Stressor in Healthy Adults: A Randomized, Double-Blind, Parallel Group, Clinical Trial. Frontiers in Nutrition [Internet]. 2021 Feb 1 [cited 2023 Nov 6];7. Available from:
https://www.frontiersin.org/articles/10.3389/fnut.2020.606124/full7. Pouchieu C, Line Pourtau, Brossaud J, Gaudout D, Jean‐Benoît Corcuff, Capuron L, et al. Acute Effect of a Saffron Extract (Safr’InsideTM) and Its Main Volatile Compound on the Stress Response in Healthy Young Men: A Randomized, Double Blind, Placebo-Controlled, Crossover Study. Nutrients [Internet]. 2023 Jun 27 [cited 2023 Nov 6];15(13):2921–1. Available from:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10346743/8. Schuster J, Mundhenke C, Nordsieck H, Pouchieu C, Pourtau L, Hahn A. Effect of a saffron extract on sleep quality in adults with moderate insomnia: A decentralized, randomized, double-blind, placebo-controlled trial. Sleep Medicine: X [Internet]. 2025 Jul 9;10:100147. Available from:
https://www.sciencedirect.com/science/article/pii/S25901427250001029. Arring NM, Millstine D, Marks LA, Nail LM. Ginseng as a Treatment for Fatigue: A Systematic Review. The Journal of Alternative and Complementary Medicine. 2018 Jul;24(7):624–33.
10. Reay JL, Scholey AB, Kennedy DO. Panax ginseng (G115) improves aspects of working memory performance and subjective ratings of calmness in healthy young adults. Human Psychopharmacology: Clinical and Experimental. 2010 Aug 19;25(6):462–71.
11. Ai Z, Cheng A, Yu YT, Yu L, Jin W. Antidepressant-Like Behavioral, Anatomical, and Biochemical Effects of Petroleum Ether Extract from Maca (Lepidium meyenii) in Mice Exposed to Chronic Unpredictable Mild Stress. Journal of Medicinal Food [Internet]. 2014 May 1 [cited 2023 Nov 7];17(5):535–42. Available from:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025608/12. Gonzales GF. Ethnobiology and Ethnopharmacology of Lepidium meyenii (Maca), a Plant from the Peruvian Highlands. Evidence-based Complementary and Alternative Medicine [Internet]. 2012 Jan 1 [cited 2023 Nov 7];2012:1–10. Available from:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184420/13. Dighriri IM, Alsubaie AM, Hakami FM, Dalal Hamithi, Maryam Mohammed Alshekh, Khobrani FA, et al. Effects of Omega-3 Polyunsaturated Fatty Acids on Brain Functions: A Systematic Review. Cureus [Internet]. 2022 Oct 9 [cited 2023 Nov 7]; Available from:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641984/14. DiNicolantonio JJ, O’Keefe JH. The Importance of Marine Omega-3s for Brain Development and the Prevention and Treatment of Behavior, Mood, and Other Brain Disorders. Nutrients [Internet]. 2020 Aug 4 [cited 2023 Nov 7];12(8):2333–3. Available from:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468918/15. Madison AA, Belury MA, Andridge R, Renna ME, M. Rosie Shrout, Malarkey WB, et al. Omega-3 supplementation, and stress reactivity of cellular aging biomarkers: an ancillary substudy of a randomized, controlled trial in midlife adults. Molecular Psychiatry [Internet]. 2021 Apr 20 [cited 2023 Nov 6];26(7):3034–42. Available from:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510994/18. Hack B, Penna EM, Talik T, Chandrashekhar R, Millard-Stafford M. Effect of Guarana (Paullinia cupana) on Cognitive Performance: A Systematic Review and Meta-Analysis. Nutrients. 2023 Jan 14;15(2):434.
19. Kennedy DO, Haskell CF, Wesnes KA, Scholey AB. Improved cognitive performance in human volunteers following administration of guarana (Paullinia cupana) extract: comparison and interaction with Panax ginseng. Pharmacology Biochemistry and Behavior. 2004 Nov;79(3):401–11.
21. Cox KHM, White DJ, Pipingas A, Poorun K, Scholey A. Further Evidence of Benefits to Mood and Working Memory from Lipidated Curcumin in Healthy Older People: A 12-Week, Double-Blind, Placebo-Controlled, Partial Replication Study. Nutrients. 2020 Jun 4;12(6):1678.